LYMPHOID NEOPLASIA Clonal evolution of adult T-cell leukemia/lymphoma takes place in the lymph nodes
نویسندگان
چکیده
1Division of Molecular Medicine, Aichi Cancer Center Research Institute, Nagoya, Japan; 2Hematology and Oncology, Mie University Graduate School of Medicine, Tsu, Japan; 3Department of Hematology, Imamura Bun-in Hospital, Kamoikeshinmachi, Kagoshima, Japan; 4Department of Hematology and Molecular Medicine Unit, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan; 5Deptment of Internal Medicine, Heartlife Hospital, Okinawa, Japan; and 6Department of Cancer Genetics, Nagoya University Graduate School of Medicine, Chikusa-ku, Nagoya, Japan
منابع مشابه
Clonal evolution of adult T-cell leukemia/lymphoma takes place in the lymph nodes.
Adult T-cell leukemia/lymphoma (ATLL) is the neoplasm caused by human T-cell leukemia virus type 1 (HTLV-1). We performed oligo-array comparative genomic hybridization (CGH) against paired samples comprising peripheral blood (PB) and lymph node (LN) samples from 13 patients with acute ATLL. We found that the genome profiles of the PB frequently differed from those of the LN samples. The results...
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تاریخ انتشار 2011